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3D HuBiogel™ vs Current 2D Assay Platforms |
Major Limitations of 2D Bioassays:
- Does not mimic Tissue Environment
- Poor Predictors of Drug Response
- Aberrant gene expression
Advantages of 3D HuBiogel Assay:
- Permits cells to grow, organize &
function as ‘Mini-tissues’
- Real-time morphological &
functional analysis
- Biomarkers & Gene expression
similar to in vivo conditions
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High Value Utility For Drug Discovery |
- Precise analysis of drug
sensitivity & toxicity
- Rapid preclinical drug
evaluation
- Accelerated functional
genomics and proteomics
research
- Patient-based therapy
response and biomarker
profiling
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Multi-Tissue Models For Drug Discovery
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- Create normal & disease
‘mini-tissues’ models
- Elucidate ‘in vivo-like’
cellular & molecular endpoints
- Parallel drug sensitivity tissue
toxicity profiling
- Defined bio-scaffolds for stem
cells & tissue repair research
- Long-term culture studies of
patient-derived cells/ biopsies
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